In a large mixing bowl, combine the ground turkey, breadcrumbs, chopped red onion, Dijon mustard, Worcestershire sauce, garlic powder, paprika, salt, and pepper. Mix until just combined; do not overwork the meat.
Divide the mixture into four equal portions and shape them into patties, about 3/4 inch thick. Make a small indentation in the center of each patty to prevent it from puffing up during cooking.
Heat a skillet or grill over medium heat and add a drizzle of olive oil. Once hot, place the turkey patties on the skillet or grill. Cook for 5-6 minutes on one side.
Carefully flip the patties and cook for an additional 5-6 minutes on the other side until the internal temperature reaches 165°F (75°C).
While the burgers are cooking, toast the burger buns lightly on the skillet or grill for added flavor and texture.
To assemble the burgers, place a lettuce leaf and a slice of tomato on the bottom half of each bun. Add the cooked turkey patty, and top with slices of avocado. Place the top half of the bun over the avocado.
Serve immediately with your favorite condiments on the side.
Notes
Make sure not to overwork the meat for tender patties.