In a large bowl, marinate the chicken tenders in buttermilk for at least 30 minutes (or up to 2 hours in the refrigerator) to ensure tenderness and flavor.
In another bowl, combine the breadcrumbs, sesame seeds, garlic powder, onion powder, salt, and pepper. Mix well to combine the dry ingredients.
In a third bowl, mix the soy sauce and honey; set aside.
Preheat your oven to 400°F (200°C) to keep the tenders warm after frying.
Remove the chicken tenders from the buttermilk marinade and let the excess drip off. Dip each tender into the soy sauce and honey mixture, then directly into the breadcrumb-sesame mixture, pressing down to ensure an even coating.
In a large skillet, heat about ½ inch of vegetable oil over medium-high heat. Once hot, carefully add the coated chicken tenders, cooking in batches if necessary to avoid overcrowding.
Fry each tender for about 3-4 minutes on each side or until golden brown and crispy. Use a slotted spoon to transfer the tenders to a plate lined with paper towels to drain excess oil.
Place the fried chicken tenders on a baking sheet and keep them warm in the preheated oven while you fry the remaining batches.
Notes
Serve on a rustic wooden board, garnished with fresh cilantro and a dipping sauce.