Preheat your oven to 225°F (110°C) to create a low and slow cooking environment, perfect for crisping the zucchini.
Line a baking sheet with parchment paper and lightly spray with cooking spray to prevent sticking.
In a large mixing bowl, combine the grated Parmesan cheese, garlic powder, onion powder, dried oregano, salt, and pepper. Mix well to ensure the spices are evenly distributed.
Add the thinly sliced zucchini to the bowl, and drizzle with one tablespoon of olive oil. Toss the zucchini so it is evenly coated with the oil and the cheese-spice mixture.
Arrange the zucchini slices in a single layer on the prepared baking sheet, making sure they are not overlapping for optimal crispiness.
Bake in the oven for about 1 hour and 15 minutes, flipping the slices halfway through. Keep an eye on them, as baking times may vary; they should be golden brown and crispy.
Once done, remove from the oven and allow the chips to cool for a few minutes before serving. They'll become even crispier as they cool.
Notes
Serve with marinara sauce or a creamy dip for added flavor.