Preheat the oven to 425°F (220°C) and line a baking sheet with parchment paper.
In a medium-sized bowl, whisk together the flour, garlic powder, onion powder, smoked paprika, salt, and pepper.
In another bowl, pour in the buttermilk (or plant-based milk).
Dip each cauliflower floret first into the buttermilk, shaking off excess, and then dredge in the flour mixture until well coated. Place the coated florets on the prepared baking sheet.
Bake in the preheated oven for 20-25 minutes, flipping halfway through, until the cauliflower is golden brown and crispy.
Remove the baking sheet from the oven and drizzle the buffalo sauce over the baked cauliflower, shaking the pan gently to coat all pieces evenly. Return to the oven and bake for an additional 5-10 minutes.
While the cauliflower is baking, warm the tortillas in a skillet over medium heat until soft and pliable.
Assemble the tacos by placing a generous amount of buffalo cauliflower on each tortilla, followed by shredded lettuce, diced tomatoes, and a sprinkle of blue cheese.
Garnish with fresh cilantro and serve lime wedges on the side for squeezing over the tacos.
Notes
For a vegan option, use plant-based milk and vegan cheese.